Description

Triphenyl-D15-Phosphine Oxide is a deuterium-labeled isotopologue of triphenylphosphine oxide, a key organophosphorus compound. This labeled version is essential for advanced analytical and research applications where tracking molecular behavior is critical. It is primarily used by researchers and scientists in pharmaceutical development, material science, and as a mechanistic probe in organic synthesis and spectroscopy.

Application

• Internal Standard for Quantitative Analysis: Used as a stable, non-interfering standard in mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy for the accurate quantification of related phosphine compounds.
• Mechanistic Studies in Catalysis: Serves as a deuterium-labeled probe to investigate reaction pathways and mechanisms in transition-metal catalyzed processes, including cross-coupling reactions.
• Pharmaceutical Research: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace the fate of phosphine-containing molecules using isotope tracing techniques.
• Polymer Science: Acts as a chain-transfer agent or stabilizer in the synthesis of specialized polymers, with the deuterium label allowing for detailed structural analysis of the polymer matrix.
• Spectroscopic Reference Material: Provides a high-purity, isotopically labeled reference for calibrating spectroscopic instruments and developing new analytical methods.

Basic Information

Product Name	Triphenyl-D15-Phosphine Oxide
CAS No.	54964-93-1
Molecular Formula	C18D15OP
Molecular Weight	283.36 g/mol
Synonyms	Deuterated Triphenylphosphine Oxide; (D15)Triphenylphosphine Oxide; Perdeuterotriphenylphosphine Oxide; TPPO-d15; Phosphine Oxide, tris(pentadeuteriophenyl)-; Hexadeuterio(perdeuteriophenyl)phosphine oxide
EINECS	Contact for details

Quality Control

Our Triphenyl-D15-Phosphine Oxide is manufactured under controlled conditions to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous analysis, including NMR and Mass Spectrometry, to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profiles is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Incorporation)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.