Description

4-Iodo-2-Methylisoquinolin-1(2H)-One is a versatile halogenated isoquinolinone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine substituent and a lactam moiety, makes it a valuable building block for constructing complex heterocyclic systems. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating organic semiconductors, liquid crystals, and photoactive polymers.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Heck) and functional group transformations in medicinal chemistry.
• Academic & Institutional R&D: Serves as a standard or starting material for methodological studies and novel heterocycle construction in university and government laboratories.

Basic Information

Product Name	4-Iodo-2-Methylisoquinolin-1(2H)-One
CAS No.	54931-61-2
Molecular Formula	C₁₀H₈INO
Molecular Weight	285.08 g/mol
Synonyms	4-Iodo-2-methyl-1(2H)-isoquinolinone; 4-Iodo-2-methylisoquinolin-1-one; 2-Methyl-4-iodo-1(2H)-isoquinolinone; 4-Iodo-2-methyl-1,2-dihydroisoquinolin-1-one; 1(2H)-Isoquinolinone, 4-iodo-2-methyl-; 54931-61-2; 4-Iodo-2-methyl-2H-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Methylisoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be performed under subdued lighting where practical.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.