Description

5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid Trimethylsilyl Ester is a key protected derivative of an indole acetic acid, serving as a crucial synthetic intermediate in advanced organic chemistry. This compound is valued for its role in facilitating complex reactions by protecting the carboxylic acid group, thereby enhancing solubility and stability in non-polar media. It is primarily sought by research and development laboratories, pharmaceutical manufacturers, and fine chemical producers engaged in the synthesis of novel indole-based compounds, including potential drug candidates and specialized agrochemicals.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel indole-based therapeutic agents, including potential anti-inflammatory and neurological drugs.
• Agrochemical Synthesis: Used in the development of advanced plant growth regulators and other specialized agrochemical products that leverage the indole acetic acid skeleton.
• Organic Synthesis Reagent: Functions as a protected carboxylic acid derivative, enabling complex multi-step synthesis in research settings where selective deprotection is required.
• Biochemical Research: Employed in studies investigating auxin analogs and other plant hormone-related biochemical pathways.
• Material Science Precursor: Serves as a starting material for the synthesis of specialized organic compounds used in advanced material applications.

Basic Information

Product Name	5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid Trimethylsilyl Ester
CAS No.	54833-72-6
Molecular Formula	C₁₅H₂₁NO₃Si
Molecular Weight	291.42 g/mol
Synonyms	5-Methoxy-2-methylindole-3-acetic acid TMS ester; 2-Methyl-5-methoxyindole-3-acetic acid trimethylsilyl ester; (5-Methoxy-2-methyl-1H-indol-3-yl)acetic acid trimethylsilyl ester; TMS ester of 5-Methoxy-2-methyl-1H-indole-3-acetic acid; 54833-72-6; Trimethylsilyl 2-(5-methoxy-2-methyl-1H-indol-3-yl)acetate
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Methyl-1H-Indole-3-Acetic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.