Description

Methyl 4-(Bromomethyl)Thiophene-2-Carboxylate is a versatile and high-value brominated thiophene derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a reactive bromomethyl group and a carboxylate ester, makes it an indispensable precursor for constructing complex heterocyclic systems and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of thiophene-containing drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides that incorporate the thiophene moiety for enhanced biological activity.
• Material Science & Organic Electronics: Serves as a monomer or precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and coordination chemistry.
• Chemical Research & Development: Utilized as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of complex fragrance and dye molecules.

Basic Information

Product Name	Methyl 4-(Bromomethyl)Thiophene-2-Carboxylate
CAS No.	54796-51-9
Molecular Formula	C7H7BrO2S
Molecular Weight	235.10 g/mol
Synonyms	2-Thiophenecarboxylic acid, 4-(bromomethyl)-, methyl ester; Methyl 4-(bromomethyl)thiophene-2-carboxylate; 4-(Bromomethyl)thiophene-2-carboxylic acid methyl ester; Methyl 5-(bromomethyl)thiophene-3-carboxylate (alternative numbering); 2-Methoxycarbonyl-4-bromomethylthiophene
EINECS	Contact for details

Quality Control

Our production of Methyl 4-(Bromomethyl)Thiophene-2-Carboxylate adheres to stringent in-process controls and final release specifications to ensure batch-to-batch consistency and high purity. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP compliance for advanced intermediates and can provide material for regulatory filings. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.