Description

L-Phenylalanine-2-D1 is a stable isotope-labeled derivative of the essential amino acid L-Phenylalanine, specifically deuterated at the 2-position. This precise labeling makes it an indispensable tool for advanced research and analytical applications where molecular tracing is required. It is primarily utilized by scientists and manufacturers in the pharmaceutical, metabolic research, and analytical chemistry sectors for use as an internal standard, tracer, or building block in deuterated compounds.

Application

• Internal Standard for Mass Spectrometry (MS): Essential for quantitative bioanalysis and metabolomics studies due to its distinct mass shift.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolic flux research to track the incorporation and fate of phenylalanine.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for method development and validation in drug testing.
• Precursor for Deuterated Compounds: Acts as a building block in the synthesis of more complex deuterated active pharmaceutical ingredients (APIs) or biochemicals.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Employed as a probe in structural and dynamic studies of proteins and peptides.
• Nutritional and Biomedical Research: Facilitates studies on amino acid metabolism, protein synthesis, and related disorders like phenylketonuria (PKU).

Basic Information

Product Name	L-Phenylalanine-2-D1
CAS No.	54793-54-3
Molecular Formula	C9H10DNO2
Molecular Weight	166.20 g/mol
Synonyms	(S)-2-Amino-3-(2-deuteriophenyl)propanoic acid; L-Phenylalanine-2-d; (2S)-2-Azaniumyl-3-(2-deuteriophenyl)propanoate; Deuterated L-Phenylalanine; L-Phe-2-d; Phenylalanine-d1 (position specific); L-β-Phenyl-α-aminopropionic acid-2-D1; (S)-Phenylalanine-2-D1
EINECS	Contact for details

Quality Control

Our L-Phenylalanine-2-D1 is manufactured under strict quality systems to ensure high isotopic and chemical purity, suitable for sensitive research applications. Each batch is characterized by advanced analytical techniques including NMR, MS, and HPLC. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D %), chemical purity, and specific tests is provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to prevent moisture uptake and maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Purity (MS)	≥ 98 atom % D (at 2-position)
Optical Rotation	[α]20/D: -33° to -37° (c=1 in H2O)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.