Description

1,2,3,5,7-Pentamethyl-1H-Indole is a highly substituted indole derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique pentamethylated structure provides steric hindrance and electronic modification, making it crucial for the development of specialized fine chemicals and functional materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its substituted indole core contributes to biological activity.
• Material Science Precursor: Serves as a monomer or functional unit in the development of organic semiconductors, conductive polymers, and advanced dyes.
• Ligand Synthesis: Utilized to create sophisticated nitrogen-containing ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Research: A valuable reference standard and starting material in academic and industrial research exploring heterocyclic chemistry and substitution effects.
• Flavor & Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals due to its stable, modified indole structure.

Basic Information

Product Name	1,2,3,5,7-Pentamethyl-1H-Indole
CAS No.	54789-37-6
Molecular Formula	C₁₃H₁₇N
Molecular Weight	187.28 g/mol
Synonyms	1H-Indole, 1,2,3,5,7-pentamethyl-; Pentamethylindole; 1,2,3,5,7-Pentamethylindole; 2,3,5,7-Tetramethyl-1-methylindole; NSC 407348; AI3-52090
EINECS	Contact for details

Quality Control

Every batch of 1,2,3,5,7-Pentamethyl-1H-Indole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results from HPLC, GC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles where applicable, supporting your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.