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4-Amino-3-Chloro (1H)Indazole CAS NO 54768-48-8


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CAS No.:54768-48-8

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Description

4-Amino-3-Chloro (1H)Indazole is a high-purity, heterocyclic aromatic building block of significant importance in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with targeted biological or material properties.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
  • Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
  • Material Science: Serves as a building block for creating advanced organic electronic materials, dyes, and pigments.
  • Biochemical Tool Compound: Employed in life science research as a scaffold for probing biological pathways and enzyme functions.
  • Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis.

Basic Information

Product Name 4-Amino-3-Chloro (1H)Indazole
CAS No. 54768-48-8
Molecular Formula C7H6ClN3
Molecular Weight 167.60 g/mol
Synonyms 3-Chloro-1H-indazol-4-amine; 4-Amino-3-chloro-1H-indazole; 3-Chloro-4-aminoindazole; 4-Amino-3-chloroindazole; 1H-Indazol-4-amine, 3-chloro-; 3-Chloroindazol-4-ylamine; 4-Amino-3-chloro-1H-indazole (9CI); 3-Chloro-1H-indazole-4-amine
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Quality Control

Our 4-Amino-3-Chloro (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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