Description

Maleic Anhydride, [1,4-14C] is a carbon-14 labeled derivative of maleic anhydride, a versatile industrial chemical intermediate. This isotopically labeled compound is essential for conducting precise metabolic, environmental, and synthetic pathway studies, providing critical data for research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for tracer applications and analytical method development.

Application

• Tracer Studies in Metabolism: Used to investigate the metabolic pathways and degradation products of maleic anhydride derivatives in biological systems.
• Polymer Research & Development: Acts as a labeled monomer for studying polymerization mechanisms, copolymer composition, and material fate in advanced polymers and resins.
• Environmental Fate Analysis: Employed to trace the environmental breakdown, adsorption, and transport of maleic anhydride-based compounds.
• Agrochemical Metabolism Studies: Critical for understanding the metabolic fate and residue analysis of agrochemicals synthesized from maleic anhydride.
• Pharmaceutical R&D: Utilized in drug discovery and development for pharmacokinetic (ADME) studies of drug candidates containing the maleic anhydride moiety.
• Analytical Reference Standard: Serves as an internal standard for quantitative analysis via techniques like Liquid Scintillation Counting (LSC) or LC-MS.
• Chemical Synthesis Mechanism Elucidation: Helps in tracing reaction pathways and intermediate formation in complex organic syntheses.

Basic Information

Product Name	Maleic Anhydride, [1,4-14C]
CAS No.	54744-91-1
Molecular Formula	C414C2H2O3
Molecular Weight	~100.06 (based on 12C; specific activity affects exact weight)
Synonyms	2,5-Furandione, [1,4-14C]; [1,4-14C]Maleic Anhydride; 14C-Labeled Maleic Anhydride; Radioactive Maleic Anhydride; Carbon-14 Maleic Anhydride; cis-Butenedioic Anhydride, [1,4-14C]; 2,5-Dioxofuran, [1,4-14C]; Toxilic Anhydride, [1,4-14C]
EINECS	For the unlabeled base compound: 203-571-6

Quality Control

Every batch of Maleic Anhydride, [1,4-14C] is produced and analyzed under strict quality protocols to ensure radiochemical purity, chemical purity, and specific activity meet exacting research standards. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as assay by HPLC, radiochemical purity by radio-HPLC or TLC, and specific activity. Our quality system is designed to support GLP-compliant research and ensure reliable, reproducible results for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, consider storage under inert atmosphere. Handle and dispose of in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity	≥ 97%
Specific Activity	Contact for details (mCi/mmol)
Solvent (if supplied as solution)	Specified on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.