Description

1H-Indole-3-Acetonitrile, 2,3-Dihydro-2-Oxo- is a specialized heterocyclic organic compound that serves as a versatile synthetic intermediate. Its core value lies in its indole-based structure, which is a privileged scaffold in medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. This high-purity building block is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds and fine chemicals in laboratory and pilot-scale production.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands, leveraging its structural similarity to natural indole alkaloids.
• Material Science: Investigated as a monomer or functional additive for creating advanced polymers with specific optical or electronic properties.

Basic Information

Product Name	1H-Indole-3-Acetonitrile, 2,3-Dihydro-2-Oxo-
CAS No.	54744-66-0
Molecular Formula	C₁₀H₈N₂O
Molecular Weight	172.18 g/mol
Synonyms	2-Oxo-2,3-dihydro-1H-indole-3-acetonitrile; 3-(Cyanomethyl)oxindole; 2,3-Dihydro-2-oxo-1H-indole-3-acetonitrile; 1H-Indole-3-acetonitrile, 2,3-dihydro-2-oxo-; Oxindole-3-acetonitrile; 3-Cyanomethyloxindole; (2-Oxo-2,3-dihydro-1H-indol-3-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Acetonitrile, 2,3-Dihydro-2-Oxo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.