Description

(16ξ)-17-Acetyloxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester is a high-purity, semi-synthetic indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of complex therapeutic agents, particularly those targeting neurological and cardiovascular pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex indole-based alkaloids and potential APIs.
• Neurological Research: Used in preclinical studies for investigating compounds with potential activity on serotonergic and other neurological receptors.
• Cardiovascular Drug Development: Serves as a precursor in research for agents that may influence blood pressure and vascular tone.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and the creation of novel chemical libraries for biological screening.
• Process Chemistry: Acts as a starting material or intermediate in scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.

Basic Information

Product Name	(16ξ)-17-Acetyloxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester
CAS No.	54725-24-5
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	Methyl (16E)-17-acetoxy-1-methylsarpagan-16-carboxylate; 1-Methylsarpagan-16-carboxylic acid, 17-(acetyloxy)-, methyl ester, (16ξ)-; 17-Acetoxy-1-methylsarpagan-16-carboxylic acid methyl ester; Ajmaline derivative intermediate; Sarpagane alkaloid ester; (16E)-17-Acetyloxy-1-methylsarpagan-16-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our (16ξ)-17-Acetyloxy-1-Methylsarpagane-16-Carboxylic Acid Methyl Ester is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant quality guidelines, and material can be supplied to meet specific customer requirements for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.