Description

17-Hydroxy-16-Methoxy-α-Methylaspidospermidine-1-Acetic Acid Methyl Ester is a complex indole alkaloid derivative, serving as a critical advanced intermediate in organic synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents, particularly those targeting neurological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for building complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential therapeutic agents, especially within the class of aspidosperma alkaloids.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new drug candidates with modified biological activity.
• Process Chemistry Development: Serves as a standard or reference material for scaling up synthetic routes in pilot plants and manufacturing.
• Academic & Institutional Research: Employed in universities and research institutes for studying alkaloid synthesis, natural product chemistry, and novel organic reactions.
• Biochemical Tool Compound: Potential use in probing biological systems and enzyme interactions due to its specific structural features.
• Fine Chemical Synthesis: Intermediate for creating specialized, high-value chemicals used in various advanced material and life science applications.

Basic Information

Product Name	17-Hydroxy-16-Methoxy-α-Methylaspidospermidine-1-Acetic Acid Methyl Ester
CAS No.	54725-05-2
Molecular Formula	C23H30N2O5
Molecular Weight	414.50 g/mol
Synonyms	Methyl (1S,12R,19S)-1-carboxy-12,19-dihydroxy-11,16-dimethoxy-2-methylaspidospermidine-3-carboxylate; 16-Methoxy-17-hydroxy-α-methylaspidospermidine-1-acetic acid methyl ester; Aspidospermidine-1-acetic acid, 17-hydroxy-16-methoxy-α-methyl-, methyl ester; Yohimbine alkaloid derivative; 54725-05-2; 17-Hydroxy-16-methoxy-α-methylaspidospermidine-1-acetic acid methyl ester
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-16-Methoxy-α-Methylaspidospermidine-1-Acetic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) documenting batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.