Description

5-Bromo-2,2,8,8-Tetramethyl-Nona-3,6-Diyne is a specialized alkyne derivative featuring a bromine substituent and multiple methyl groups, offering a unique combination of reactivity and steric bulk. This compound serves as a valuable advanced synthetic intermediate for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting complex organic molecules.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and plant growth regulators that require structurally sophisticated intermediates.
• Material Science Research: Serves as a precursor for the development of specialty polymers, dendrimers, or organic electronic materials due to its rigid alkyne backbone.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Potential starting material for synthesizing novel ligands or organometallic catalysts used in asymmetric synthesis.
• Academic & Industrial R&D: A versatile reagent for methodological studies in organic synthesis and for creating compound libraries in high-throughput screening.

Basic Information

Product Name	5-Bromo-2,2,8,8-Tetramethyl-Nona-3,6-Diyne
CAS No.	54623-67-5
Molecular Formula	C₁₃H₁₉Br
Molecular Weight	255.19 g/mol
Synonyms	5-Bromo-2,2,8,8-tetramethylnona-3,6-diyne; 3,6-Nonadiyne, 5-bromo-2,2,8,8-tetramethyl-; 5-Bromo-2,2,8,8-tetramethyl-3,6-nonadiyne; 2,2,8,8-Tetramethyl-5-bromonona-3,6-diyne
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,2,8,8-Tetramethyl-Nona-3,6-Diyne is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatographic purity assays and structural confirmation, to ensure it meets the high-purity standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.