Description

2-Amidinothiophene Hydrochloride is a high-purity organic building block and pharmaceutical intermediate of significant commercial and research interest. Its value lies in its functionalized thiophene core, which serves as a versatile scaffold for synthesizing more complex heterocyclic compounds. This material is primarily sought by the pharmaceutical, agrochemical, and specialty chemical industries for applications in drug discovery, material science, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Chemical Synthesis Building Block: Serves as a versatile starting material for constructing complex heterocyclic frameworks in medicinal and combinatorial chemistry.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, conductive polymers, and advanced functional materials due to the thiophene structure.
• Biochemical Research: Employed in academic and industrial R&D for studying enzyme inhibitors and probing biological pathways.

Basic Information

Product Name	2-Amidinothiophene Hydrochloride
CAS No.	54610-70-7
Molecular Formula	C5H7N2S•HCl
Molecular Weight	162.65 g/mol
Synonyms	2-Thiophenecarboximidamide, hydrochloride; 2-Carbamimidoylthiophene hydrochloride; 2-Thiophenecarboxamidine hydrochloride; 2-Amidinothiophene HCl; 2-Thienylamidine hydrochloride; 2-(Aminoiminomethyl)thiophene hydrochloride; 2-Cyanamidinothiophene hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amidinothiophene Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, residual solvent analysis, and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.