Description

1-Chloro-3-Methanesulfonyl-Propane is a versatile organic building block featuring both a reactive chloroalkyl group and a methanesulfonyl (mesyl) moiety. This bifunctional nature makes it a valuable intermediate for the synthesis of more complex molecules in pharmaceutical and agrochemical research. It is particularly sought after by R&D chemists and process development scientists for constructing sulfonamide derivatives and other functionalized compounds. The compound is supplied to meet the stringent quality requirements of advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing sulfonamide functional groups.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Chemical Research & Development: Serves as a versatile electrophile in alkylation reactions and for introducing the methanesulfonyl group into target molecules.
• Ligand and Catalyst Preparation: Useful for modifying ligands or creating functionalized linkers in catalyst design and material science.
• Polymer Modification: Can be employed to introduce reactive sites or specific functional groups into polymer chains.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke chemical synthesis for clients.

Basic Information

Product Name	1-Chloro-3-Methanesulfonyl-Propane
CAS No.	54533-11-8
Molecular Formula	C4H9ClO2S
Molecular Weight	156.63 g/mol
Synonyms	3-Chloropropyl methyl sulfone; 1-Chloro-3-(methylsulfonyl)propane; Methyl 3-chloropropyl sulfone; 3-(Methylsulfonyl)-1-chloropropane; NSC 403119; 3-Chloro-1-(methylsulfonyl)propane
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Methanesulfonyl-Propane is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.