Description

n-Chloromethyl-4-Nitrophthalimide is a versatile and high-value organic intermediate characterized by its reactive chloromethyl and electron-withdrawing nitro groups. This compound matters for its critical role in the synthesis of complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a phthalimide or amine functional group after deprotection.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the nitrophthalimide moiety can contribute to biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the development of specialty polymers, such as polyimides, with potential applications in high-performance materials.
• Dye and Pigment Manufacturing: Acts as a precursor in the synthesis of complex organic dyes and pigments, leveraging the nitro group for color development.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new organic reactions and creating novel chemical entities for various applications.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands or catalyst components used in asymmetric synthesis and other catalytic processes.

Basic Information

Product Name	n-Chloromethyl-4-Nitrophthalimide
CAS No.	54455-34-4
Molecular Formula	C9H5ClN2O4
Molecular Weight	240.60 g/mol
Synonyms	4-Nitro-N-(chloromethyl)phthalimide; N-Chloromethyl-4-nitrophthalimide; 1-Chloromethyl-4-nitrophthalimide; 4-Nitrophthalimide N-chloromethyl derivative; (4-Nitro-1,3-dioxoisoindolin-2-yl)methyl chloride; 2-(Chloromethyl)-4-nitroisoindoline-1,3-dione
EINECS	Contact for details

Quality Control

Every batch of n-Chloromethyl-4-Nitrophthalimide is produced and tested under a strict quality management system to ensure consistency and reliability for your synthetic processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.