Description

Malonic Acid-2-14C Sodium Salt is a carbon-14 labeled derivative of malonic acid, a critical intermediate in biochemical pathways. This isotopically labeled compound is essential for conducting precise metabolic and pharmacokinetic studies, enabling researchers to trace the fate of molecules in complex biological systems. It is primarily utilized by scientists and manufacturers in the fields of pharmaceutical research, agrochemical development, and advanced material science for radiotracer applications.

Application

• Radiotracer Synthesis: A key precursor for the synthesis of carbon-14 labeled compounds for use in Absorption, Distribution, Metabolism, and Excretion (ADME) studies.
• Metabolic Pathway Analysis: Used to investigate the Krebs cycle (citric acid cycle) and other biochemical pathways in plant, animal, and microbial systems.
• Pharmaceutical Research: Critical for labeling potential drug candidates to study their metabolic stability, bioavailability, and clearance mechanisms.
• Agrochemical Development: Employed in the development and environmental fate studies of new pesticides and herbicides.
• Biochemical Mechanism Studies: Facilitates research into enzyme mechanisms, particularly those involving decarboxylation reactions.
• Material Science Research: Can be used in the development and study of novel polymers and organic materials where carbon tracking is required.

Basic Information

Product Name	Malonic Acid-2-14C Sodium Salt
CAS No.	54440-89-0
Molecular Formula	C3H3NaO4 (with C-14 at position 2)
Molecular Weight	~130.04 g/mol (specific activity dependent)
Synonyms	2-14C-Malonic Acid Disodium Salt; Sodium Malonate-2-14C; [2-14C]Malonic Acid Disodium Salt; Propanedioic Acid-2-14C Disodium Salt; Disodium Malonate-2-14C; Carbon-14 Labeled Malonic Acid Sodium Salt; Malonic-2-14C Acid Sodium Salt
EINECS	Contact for details

Quality Control

Every batch of Malonic Acid-2-14C Sodium Salt is manufactured and analyzed under strict quality systems to ensure the highest standards of radiochemical purity, chemical purity, and specific activity. Our quality protocols are designed to meet the rigorous demands of research and regulatory submission. Certificates of Analysis (COA) detailing specific activity, purity by HPLC, radiochemical purity, and solvent content are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Handle and store in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Specific Activity	Customizable (mCi/mmol)
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Solvent Content (Residual Solvents)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.