Description

Propanoic Acid, 3-(Triphenylphosphoranylidene)-, Ethyl Ester is a specialized Wittig reagent, a key intermediate in organic synthesis for the formation of carbon-carbon double bonds. This compound matters for its ability to facilitate the precise and efficient construction of complex molecules, particularly in the synthesis of alkenes, pharmaceuticals, and advanced materials. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, reliable building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A critical reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing alkene-containing molecular frameworks.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides where specific alkene functionalities are required.
• Fine Chemical & Specialty Chemical Production: Employed in the manufacture of complex organic molecules, including flavors, fragrances, and liquid crystals.
• Academic & Industrial R&D: A fundamental tool in research laboratories for method development and the exploration of new synthetic pathways.
• Material Science: Used in the synthesis of organic semiconductors, polymers, and other advanced materials with tailored properties.
• Olefination Reactions: Specifically utilized in Wittig and related olefination reactions to convert carbonyl compounds into alkenes with high stereoselectivity control.

Basic Information

Product Name	Propanoic Acid, 3-(Triphenylphosphoranylidene)-, Ethyl Ester
CAS No.	54356-04-6
Molecular Formula	C23H21O2P
Molecular Weight	360.39 g/mol
Synonyms	(Carbethoxymethylene)triphenylphosphorane; Ethyl (Triphenylphosphoranylidene)acetate; Ethyl 2-(Triphenylphosphoranylidene)acetate; Ethyl (triphenylphosphoranylidene)ethanoate; Wittig reagent - Ethyl (triphenylphosphoranylidene)acetate; ETPPA; Ethyl triphenylphosphonium acetate ylide
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3-(Triphenylphosphoranylidene)-, Ethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to confirm identity, purity, and performance. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	156 - 160 °C
Loss on Drying	≤ 1.0 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.