Description

(3Ar,7Aα)-3A,4,5,6,7,7A-Hexahydro-4β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione is a high-purity, synthetically derived isoindole derivative with a complex stereochemical configuration. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and other specialized drug candidates.
• Asymmetric Synthesis: Utilized as a building block in stereoselective synthesis to introduce specific chiral centers into complex molecular architectures.
• Organic Chemistry Research: Serves as a model compound or starting material in academic and industrial research exploring new synthetic methodologies and reaction pathways.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including catalysts, ligands, and other performance materials requiring precise stereochemistry.
• Agrochemical R&D: Potential use as an intermediate in the development of novel, enantiomerically pure agrochemicals such as herbicides or pesticides.

Basic Information

Item	Details
Product Name	(3Ar,7Aα)-3A,4,5,6,7,7A-Hexahydro-4β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione
CAS No.	54346-16-6
Molecular Formula	C₁₅H₁₇NO₃
Molecular Weight	259.30 g/mol
Synonyms	4β-Hydroxy-3aα-methyl-2-phenyl-perhydroisoindole-1,3-dione; (3aR,7aS)-3a,4,5,6,7,7a-Hexahydro-4-hydroxy-3a-methyl-2-phenyl-1H-isoindole-1,3(2H)-dione; 2-Phenyl-4-hydroxy-3a-methyl-perhydroisoindole-1,3-dione; 54346-16-6; 4-Hydroxy-3a-methyl-2-phenyl-perhydroisoindole-1,3-dione; (3aR,7aS)-4-Hydroxy-3a-methyl-2-phenyloctahydro-1H-isoindole-1,3(2H)-dione
EINECS	Contact for details

Quality Control

Our (3Ar,7Aα)-3A,4,5,6,7,7A-Hexahydro-4β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione is produced under a strict quality management system. Each batch undergoes rigorous analytical testing including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via spectroscopic methods. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications to ensure compliance with your research and manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.