Description

(3As)-3A,6,7,7Aα-Tetrahydro-7β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione is a high-purity, complex organic intermediate characterized by its unique isoindole-1,3-dione core structure. This compound is of significant commercial interest for its role as a critical building block in advanced pharmaceutical synthesis and fine chemical manufacturing. It is primarily sought after by research institutions and industrial producers engaged in the development of novel active pharmaceutical ingredients (APIs) and specialty organic compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of complex drug molecules, particularly those targeting neurological and inflammatory pathways.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes for constructing complex polycyclic frameworks due to its reactive functional groups.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective synthesis.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals for agrochemical and material science applications.
• Academic & Industrial R&D: Used in chemical research for method development and exploring new reaction pathways involving isoindole derivatives.

Basic Information

Product Name	(3As)-3A,6,7,7Aα-Tetrahydro-7β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione
CAS No.	54346-14-4
Molecular Formula	C₁₅H₁₅NO₃
Molecular Weight	257.29 g/mol
Synonyms	7β-Hydroxy-3aα-methyl-2-phenyl-cis-perhydroisoindole-1,3-dione; (3aR,7R,7aS)-7-Hydroxy-3a-methyl-2-phenyl-3a,6,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione; 3a,6,7,7a-Tetrahydro-7β-hydroxy-3aα-methyl-2-phenyl-1H-isoindole-1,3(2H)-dione; (3aS,6R,7R,7aR)-7-Hydroxy-3a-methyl-2-phenyl-3a,6,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione; cis-7-Hydroxy-3a-methyl-2-phenyl-perhydroisoindole-1,3-dione; 54346-14-4; Phenyl-substituted hydroxy-isoindoledione.
EINECS	Contact for details

Quality Control

Our (3As)-3A,6,7,7Aα-Tetrahydro-7β-Hydroxy-3Aα-Methyl-2-Phenyl-1H-Isoindole-1,3(2H)-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed after opening to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.