Description

[(2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinyl)methyl]amine dihydrochloride is a high-purity organic salt derivative of a tetrahydroisoquinoline scaffold, a structure of significant interest in medicinal chemistry. This compound serves as a critical building block (advanced intermediate) for the research and development of novel pharmaceutical agents, particularly those targeting the central nervous system. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of potential therapeutic compounds, including neuroactive agents and receptor modulators.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new drug candidates.
• Chemical Synthesis: Serves as a versatile amine component in amide coupling reactions, reductive aminations, and other transformations to construct complex molecular architectures.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical products.
• Biochemical Tool Compound: Potential use in pharmacological assays to study specific biological pathways and enzyme interactions.

Basic Information

Product Name	[(2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinyl)methyl]amine dihydrochloride
CAS No.	54329-62-3
Molecular Formula	C11H18Cl2N2
Molecular Weight	249.18 g/mol
Synonyms	1-(Aminomethyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride; 2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinemethanamine dihydrochloride; (2-Methyl-3,4-dihydro-1H-isoquinolin-3-yl)methanamine dihydrochloride; 3-(Aminomethyl)-2-methyl-1,2,3,4-tetrahydroisoquinoline dihydrochloride; TMQ Amine Dihydrochloride; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our [(2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinyl)methyl]amine dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and cGMP-grade production to meet the stringent requirements of pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.