Description

2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is a versatile tetrahydroisoquinoline derivative, a key chiral building block in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure which serves as a privileged scaffold for constructing complex molecules with high biological relevance. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of potential drug candidates targeting neurological disorders, cardiovascular diseases, and cancer.
• Agrochemical Research: Used as a building block in the development of new herbicides, fungicides, and plant growth regulators.
• Asymmetric Synthesis: Employed as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Fine Chemical Production: A precursor for the manufacture of specialty chemicals, dyes, and advanced materials.

Basic Information

Product Name	2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid
CAS No.	54329-54-3
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	2-Methyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid; 2-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; 3-Carboxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; (3S)-2-Methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (for enantiomer); MTIQ; 2-Methyl-TIQ-3-COOH; 1,2,3,4-Tetrahydro-2-methyl-3-isoquinolinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,2,3,4-Tetrahydro-Isoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiopure grade)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.