Description

(+)-15(S)-Cloprostenol CAS NO 54276-22-1 is a highly potent synthetic prostaglandin analog, specifically the biologically active stereoisomer of cloprostenol. This compound is valued for its targeted biological activity and high purity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily sought after by manufacturers and researchers in the veterinary pharmaceutical and advanced life sciences sectors for developing therapeutic agents.

Application

• Veterinary Pharmaceuticals: As a key active pharmaceutical ingredient (API) or intermediate in the formulation of drugs for animal reproduction management, particularly for estrus synchronization and induction of parturition in livestock.
• Biochemical Research: Used as a high-purity reference standard and tool compound in pharmacological studies to investigate prostaglandin receptor (FP receptor) activity and signaling pathways.
• Advanced Synthetic Chemistry: Serves as a crucial chiral building block for the synthesis of more complex prostaglandin derivatives and analogs with potential therapeutic applications.
• Veterinary Diagnostics: Employed in the development and calibration of diagnostic assays for monitoring reproductive health and hormonal levels in animals.

Basic Information

Product Name	(+)-15(S)-Cloprostenol
CAS No.	54276-22-1
Molecular Formula	C22H29ClO6
Molecular Weight	424.91 g/mol
Synonyms	(+)-Cloprostenol; 15(S)-Cloprostenol; (15S)-Cloprostenol; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E,3S)-3-hydroxy-4-(3-chlorophenoxy)-1-butenyl]cyclopentyl]-5-heptenoic Acid; Cloprostenol Impurity C (EP); Cloprostenol Related Compound C (USP); PGF2α analog; ICI 80996 (stereoisomer)
EINECS	Contact for details

Quality Control

Our (+)-15(S)-Cloprostenol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and the absence of critical impurities. Certificates of Analysis (COA) detailing chromatographic purity, assay, and related substances are provided and can be tailored to meet specific pharmacopeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store unopened vials at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For short-term use, the material may be stored at 2-8°C. The container should be allowed to reach room temperature before opening to minimize moisture condensation. Store in a well-ventilated, dry place away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (15S-isomer)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.