Description

Mabuterolhydrochloride CAS NO 54240-36-7 is a selective β2-adrenergic receptor agonist, primarily utilized as a key pharmaceutical intermediate in the synthesis of advanced therapeutic agents. Its significance lies in its role as a critical building block for developing bronchodilators and other specialized medications targeting respiratory conditions. This high-purity compound is essential for pharmaceutical manufacturers and research institutions engaged in drug development, formulation, and analytical chemistry.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of active pharmaceutical ingredients (APIs) for respiratory medications.
• Bronchodilator Research: Serves as a key compound in the research and development of new β2-adrenergic agonists for treating asthma and chronic obstructive pulmonary disease (COPD).
• Analytical Reference Standard: Used as a certified reference material (CRM) in quality control laboratories for HPLC, LC-MS, and other analytical methods to ensure product purity and identity.
• Preclinical & Clinical Studies: Employed in pharmacological and toxicological studies to investigate metabolic pathways and therapeutic efficacy.
• Formulation Development: Utilized in the development of stable and effective dosage forms, such as inhalers and tablets.
• Chemical Synthesis: Acts as a versatile intermediate for further chemical modifications to create novel derivatives with potential therapeutic value.

Basic Information

Product Name	Mabuterolhydrochloride
CAS No.	54240-36-7
Molecular Formula	C13H19Cl2N3O2
Molecular Weight	328.21 g/mol
Synonyms	Mabuterol HCl; 4-Amino-3-chloro-α-[[(1,1-dimethylethyl)amino]methyl]-5-(trifluoromethyl)benzenemethanol hydrochloride; Mabuterol Hydrochloride; Mabuterol HCL; Mabuterol HCl Salt; (RS)-Mabuterol hydrochloride; α-[(tert-Butylamino)methyl]-3-chloro-4-amino-5-(trifluoromethyl)benzyl alcohol hydrochloride
EINECS	Contact for details

Quality Control

Our Mabuterolhydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We adhere to ICH guidelines and relevant pharmaceutical standards for intermediates. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤1.5%; Any single impurity ≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.