Description

Salbutamol Acetonide is a synthetic corticosteroid derivative, specifically an acetonide prodrug of the bronchodilator salbutamol. This compound is of significant interest in pharmaceutical research and development for its potential to modify the pharmacokinetic profile and enhance the therapeutic efficacy of the parent drug. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of advanced respiratory and anti-inflammatory medications, where controlled release and targeted delivery are critical.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of specialized corticosteroid-based active pharmaceutical ingredients (APIs).
• Respiratory Drug Research: Used in R&D for developing novel prodrug formulations of salbutamol aimed at improving lung bioavailability and duration of action.
• Anti-inflammatory Agent Development: Investigated for its potential corticosteroid activity in topical or inhalable formulations for treating inflammation.
• Analytical Reference Standard: Serves as a high-purity standard in quality control laboratories for HPLC, GC, or spectroscopic analysis of related compounds.
• Chemical Synthesis: Employed in organic synthesis for introducing the salbutamol acetonide moiety into more complex molecular architectures.

Basic Information

Product Name	Salbutamol Acetonide
CAS No.	54208-72-9
Molecular Formula	C15H21NO4
Molecular Weight	279.33 g/mol
Synonyms	Albuterol Acetonide; 1-(3,3-Dimethyl-2-oxobutyl)-4-[(1,1-dimethylethyl)amino]methyl]-1,3-benzenediol; Salbutamol 16,17-Acetonide; 5-[2-(tert-Butylamino)-1-hydroxyethyl]-2-hydroxyphenyl 2,2-dimethylpropanoate (tautomeric form); (RS)-Salbutamol Acetonide
EINECS	Contact for details

Quality Control

Our Salbutamol Acetonide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a Certificate of Analysis (COA) detailing specifications and test results, available upon request. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in global supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.