Description

Methyl 4-(Aminomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate is a high-value, multifunctional bicyclic organic compound featuring both an ester and a primary amine group. This unique structure makes it a versatile and critical building block in advanced organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold or precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its rigid bicyclic framework.
• Ligand and Catalyst Development: The aminomethyl group is ideal for creating chelating ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for producing specialty polymers with enhanced thermal or mechanical properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and constructing complex natural product analogs.
• Peptidomimetics: The rigid bicyclo[2.2.2]octane core is used as a conformationally restricted surrogate for amino acids in peptide-based drug design.

Basic Information

Product Name	Methyl 4-(Aminomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	54202-09-4
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	1-Carbomethoxy-4-(aminomethyl)bicyclo[2.2.2]octane; Methyl 4-(aminomethyl)bicyclo[2.2.2]octane-1-carboxylate; 4-(Aminomethyl)bicyclo[2.2.2]octane-1-carboxylic acid methyl ester; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-(aminomethyl)-, methyl ester; 1-(Methoxycarbonyl)-4-(aminomethyl)bicyclo[2.2.2]octane; 4-Aminomethyl-1-methoxycarbonylbicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our Methyl 4-(Aminomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.