Description

5-Fluoro-2,3,3-Trimethyl-3H-Indole is a specialized fluorinated indole derivative, a key building block in advanced organic synthesis. This compound matters for its role as a crucial intermediate in the development of pharmaceuticals, agrochemicals, and functional materials, where its unique fluorine-substituted indole core imparts desirable biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Research: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as OLEDs (Organic Light-Emitting Diodes) and conductive polymers.
• Dye and Pigment Manufacturing: Acts as a key intermediate for synthesizing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.
• Academic & Industrial R&D: Employed in exploratory chemistry for developing new synthetic methodologies and creating libraries of novel fluorinated heterocyclic compounds.

Basic Information

Product Name	5-Fluoro-2,3,3-Trimethyl-3H-Indole
CAS No.	54136-23-1
Molecular Formula	C11H12FN
Molecular Weight	177.22 g/mol
Synonyms	5-Fluoro-2,3,3-trimethylindole; 3H-Indole, 5-fluoro-2,3,3-trimethyl-; 2,3,3-Trimethyl-5-fluoro-3H-indole; 5-Fluoro-2,3,3-trimethylindolenine; 5-Fluoro-2,3,3-trimethyl-1H-indole (tautomer); FTMI (abbreviation); 5-Fluoro-2,3,3-trimethylindolenin
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2,3,3-Trimethyl-3H-Indole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO 9001 standards where required for your applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.