Description

1,3-Dibromoisoquinoline is a versatile brominated heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its value lies in its dual bromine substituents, which provide distinct reactive sites for selective cross-coupling and functionalization reactions. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates, particularly those with isoquinoline-based scaffolds for therapeutic applications.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, where the bromine atoms allow for the introduction of specific bioactive moieties.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-heteroatom bonds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Ligand Preparation: Intermediate for the synthesis of specialized ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	1,3-Dibromoisoquinoline
CAS No.	53987-60-3
Molecular Formula	C9H5Br2N
Molecular Weight	286.95 g/mol
Synonyms	Isoquinoline, 1,3-dibromo-; 1,3-Dibromo-isoquinoline; 53987-60-3; 1,3-DBIQ; NSC 403120; Dibromoisoquinoline; 1,3-Dibromoisochinolin
EINECS	Contact for details

Quality Control

Our 1,3-Dibromoisoquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, to meet exacting customer specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.