Description

13-Propylberberine is a semi-synthetic derivative of the natural alkaloid berberine, characterized by the addition of a propyl group at the 13-position. This structural modification is designed to enhance its bioavailability and pharmacological activity compared to the parent compound. It is a compound of significant interest for research and development in the pharmaceutical and nutraceutical sectors, targeting applications in metabolic and inflammatory pathways. The product is supplied as a high-purity reference standard and active ingredient for advanced studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) for investigating new therapeutic agents.
• Metabolic Disorder Studies: Used in preclinical research targeting conditions like diabetes, obesity, and non-alcoholic fatty liver disease (NAFLD).
• Anti-inflammatory Agent Development: Explored for its potential efficacy in modulating inflammatory pathways and related disorders.
• Nutraceutical Formulation: Incorporated into advanced dietary supplement prototypes aimed at metabolic health support.
• Biochemical Research: Employed as a specific inhibitor or modulator in enzymatic and cellular signaling studies.
• Reference Standard: Provides a certified high-purity material for analytical method development, validation, and quality control in laboratories.

Basic Information

Product Name	13-Propylberberine
CAS No.	53912-47-3
Molecular Formula	C23H23NO4
Molecular Weight	377.44 g/mol
Synonyms	13-Propylberberine; Berberine, 13-propyl-; 13-n-Propylberberine; 13-Propyl-9,10-dimethoxy-5,6-dihydro-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinolin-7-ium; 13-Propylberberine chloride (common salt form); Propylberberine
EINECS	Contact for details

Quality Control

Our 13-Propylberberine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.