Description

Cloprostenol Lactone Diol is a key synthetic intermediate in the production of prostaglandin analogs. This compound is of significant commercial importance due to its role in the manufacture of potent veterinary and pharmaceutical active ingredients. It is primarily required by manufacturers in the animal health and pharmaceutical industries for the synthesis of prostaglandin-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of Cloprostenol sodium and other prostaglandin F2α analogs used in veterinary medicine.
• Veterinary Drug Synthesis: Essential for manufacturing products that regulate the reproductive cycle in livestock, such as estrus synchronization and parturition induction agents.
• Prostaglandin Analog Production: Serves as a precursor for a range of prostaglandin derivatives with various biological activities.
• Research & Development: Used in biochemical and pharmacological research to study prostaglandin pathways and develop new therapeutic agents.
• Fine Chemical Manufacturing: Employed in controlled, multi-step organic synthesis processes requiring high-purity intermediates.
• API (Active Pharmaceutical Ingredient) Production: A key starting material or intermediate in the GMP-compliant production of final drug substances.

Basic Information

Product Name	Cloprostenol Lactone Diol
CAS No.	53906-54-0
Molecular Formula	C22H29ClO6
Molecular Weight	424.92 g/mol
Synonyms	(5Z)-7-[(1R,2R,3R,5S)-2-[(1E,3R)-4-(3-Chlorophenoxy)-3-hydroxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid γ-lactone; Cloprostenol Impurity C; Cloprostenol Intermediate; PGF2α analog intermediate; 9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oic acid γ-lactone (partial); Prostamate intermediate; Estrumate intermediate
EINECS	Contact for details

Quality Control

Our Cloprostenol Lactone Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.