Description

Carbobenzyloxyglycyl-L-Tryptophan Methyl Ester is a protected dipeptide derivative, specifically the methyl ester of the Cbz-Gly-Trp-OH sequence. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic peptides and conducting biochemical studies.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the controlled assembly of longer, complex peptide sequences in both research and GMP-scale production.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs targeting various diseases.
• Bioconjugation & Probe Development: Acts as a precursor for creating fluorescently labeled or biotinylated peptides for diagnostic and imaging applications.
• Enzyme Substrate & Inhibitor Studies: Employed in biochemical assays to study protease activity or to develop specific enzyme inhibitors.
• Academic & Industrial R&D: A fundamental reagent for exploring peptide structure-activity relationships (SAR) and new synthetic methodologies.

Basic Information

Product Name	Carbobenzyloxyglycyl-L-Tryptophan Methyl Ester
CAS No.	53880-82-3
Molecular Formula	C23H25N3O5
Molecular Weight	423.47 g/mol
Synonyms	Cbz-Gly-Trp-OMe; Z-Gly-Trp-OMe; N-Carbobenzyloxyglycyl-L-tryptophan methyl ester; Benzyl N-[2-[[(2S)-1-methoxy-1-oxo-3-(1H-indol-3-yl)propan-2-yl]amino]-2-oxoethyl]carbamate; Z-Gly-Tryptophan-OMe; Cbz-Gly-Tryptophan Methyl Ester; Nα-Carbobenzyloxyglycyl-L-tryptophan methyl ester
EINECS	Contact for details

Quality Control

Our Carbobenzyloxyglycyl-L-Tryptophan Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research and peptide synthesis. Certificates of Analysis (COA) with detailed specifications are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.