Description

Dl-Alanine-3,3,3-D3 is a stable isotope-labeled analog of the amino acid alanine, where three hydrogen atoms are replaced by deuterium at the 3-position. This deuteration is critical for applications requiring precise molecular tracking and reduced signal interference in spectroscopic analysis. It serves as an essential building block and internal standard for researchers and manufacturers in the pharmaceutical, analytical chemistry, and metabolic research sectors who require high-purity, isotopically enriched materials.

Application

• NMR Spectroscopy: Used as an internal standard or chemical shift reference in Nuclear Magnetic Resonance studies due to its distinct deuterium signature.
• Mass Spectrometry: Employed as a stable isotope-labeled internal standard for the accurate quantification of alanine and related compounds in complex biological matrices.
• Metabolic Pathway Tracing: A vital tool in biomedical and biochemical research for tracing metabolic fluxes and studying protein and amino acid metabolism using deuterium labeling.
• Pharmaceutical Development: Utilized in the synthesis of deuterated drug candidates, where deuterium incorporation can alter pharmacokinetic profiles (deuterated drugs).
• Analytical Reference Standards: Serves as a high-purity certified reference material (CRM) for calibrating analytical instruments and validating methods.
• Biochemical Research: Applied in enzyme kinetics studies and mechanistic investigations where tracking the fate of specific hydrogen atoms is necessary.

Basic Information

Product Name	Dl-Alanine-3,3,3-D3
CAS No.	53795-94-1
Molecular Formula	C₃H₄D₃NO₂
Molecular Weight	92.11 g/mol
Synonyms	DL-Alanine-d3; (RS)-2-Aminopropanoic-3,3,3-d3 acid; Alanine-3,3,3-d3; (±)-Alanine-3,3,3-d3; DL-2-Aminopropionic-3,3,3-d3 acid; Deuterated DL-Alanine; DL-Alanine (3,3,3-D3); NSC 206864-d3
EINECS	Contact for details

Quality Control

Our Dl-Alanine-3,3,3-D3 is manufactured under strict quality systems. Each batch is subjected to rigorous analytical testing, including NMR and Mass Spectrometry, to confirm isotopic enrichment (D-enrichment typically >98 atom % D) and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.