Description

n-Butane-1,4-D2 is a deuterium-labeled isotopologue of n-butane, specifically deuterated at both terminal methylene positions. This compound is a valuable stable isotope-labeled standard, essential for ensuring accuracy and traceability in advanced analytical techniques. It is primarily utilized by research scientists and quality control laboratories in the pharmaceutical, agrochemical, and material science sectors for applications requiring precise internal standards or mechanistic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference in GC-MS and LC-MS analyses to improve accuracy in pharmaceutical metabolite profiling and environmental testing.
• NMR Spectroscopy Solvent & Reagent: Serves as a deuterated reagent or solvent component in nuclear magnetic resonance (NMR) studies for mechanistic investigation and structural elucidation.
• Chemical Synthesis Intermediate: Acts as a specialized building block for synthesizing deuterium-labeled complex molecules in medicinal chemistry and material research.
• Metabolic Pathway Tracing: Employed in biochemical and pharmacological research to trace metabolic pathways and study drug distribution using isotope effects.
• Polymer Science Research: Used in the development and analysis of novel polymeric materials where deuterium labeling provides contrast in scattering techniques.
• Calibration Standard: Provides a certified reference material for calibrating analytical instruments in regulated laboratory environments.

Basic Information

Product Name	n-Butane-1,4-D2
CAS No.	53716-54-4
Molecular Formula	C4H8D2
Molecular Weight	60.13 g/mol
Synonyms	1,1,4,4-Tetradeuteriobutane; Butane-1,4-d2; [1,4-2H2]Butane; 1,4-Dideuterobutane; n-Butane-d2 (asymmetric); Deuterated Butane; Butane-1,1,4,4-d4 (common mislabeling); Isotopic Butane
EINECS	Contact for details

Quality Control

Every batch of n-Butane-1,4-D2 is produced and analyzed under strict quality management protocols to ensure isotopic and chemical purity meets the exacting requirements of research and analytical applications. Our products undergo rigorous quality testing, including isotopic enrichment analysis by NMR and GC-MS. Certificates of Analysis (COA) detailing batch-specific purity, isotopic content, and analytical methods are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and ignition points. Due to its gaseous state under standard conditions, it is typically supplied in sealed, pressurized cylinders or ampoules. Handle and store in accordance with all local and international regulations for compressed gases.

Specification

Item	Specification
Appearance (Visual)	Colorless Gas
Identification (IR / NMR)	Conforms to Structure
Isotopic Purity (D, min)	98.0 atom % D
Chemical Purity (GC, min)	99.0%
Isotopic Enrichment (Position 1 & 4, min)	98.0 atom % D

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.