Description

4-Bromo-3-Formylthiophene-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique structure, featuring both a carboxylic acid and a formyl group on a brominated thiophene core, enables precise molecular construction in complex chemical environments. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection agents, leveraging the thiophene moiety for bioactivity.
• Organic Electronic Materials: Serves as a building block for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: The carboxylic acid and aldehyde functionalities allow for the creation of complex chelating ligands for metal catalysis.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science research, enabling structure-activity relationship (SAR) studies.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	4-Bromo-3-Formylthiophene-2-Carboxylic Acid
CAS No.	53685-98-6
Molecular Formula	C6H3BrO3S
Molecular Weight	235.06 g/mol
Synonyms	2-Bromo-5-formylthiophene-3-carboxylic acid; 3-Formyl-4-bromothiophene-2-carboxylic acid; 4-Bromo-3-formyl-2-thiophenecarboxylic acid; 4-Bromo-3-thiophenecarboxaldehyde-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-bromo-3-formyl-; 4-Bromo-3-formylthiophene-2-carboxylic acid; 4-Bromo-3-thiophenecarboxaldehyde-2-carboxylic acid; 4-Bromo-3-formyl-2-thiophenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Formylthiophene-2-Carboxylic Acid undergoes rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency from batch to batch. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. Due to its sensitivity, the container should be kept tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.