Description

1-o-Tolyl-1H-Tetrazole-5-Thiol (CAS NO 53662-42-3) is a versatile heterocyclic compound belonging to the tetrazole-thiol class, valued for its role as a key synthetic intermediate and ligand. Its structure makes it particularly significant in the development of pharmaceuticals, agrochemicals, and advanced materials. This product is essential for research chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the tetrazole moiety into their molecular designs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs containing tetrazole rings, which are known as bioisosteres for carboxylic acids.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the tetrazole group can enhance biological activity and stability.
• Coordination Chemistry & Catalysis: Serves as a ligand for metal complexes in catalytic applications and material science due to its sulfur and nitrogen donor atoms.
• Polymer Chemistry: Acts as a modifier or cross-linking agent in the development of specialty polymers and resins with specific thermal or chemical resistance properties.
• Corrosion Inhibition: Investigated for use in formulations designed to protect metals, leveraging the adsorption properties of the thiol group.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new chemical reactions and synthesizing novel heterocyclic compounds.

Basic Information

Item	Details
Product Name	1-o-Tolyl-1H-Tetrazole-5-Thiol
CAS No.	53662-42-3
Molecular Formula	C8H8N4S
Molecular Weight	192.24 g/mol
Synonyms	5-Mercapto-1-o-tolyl-1H-tetrazole; 1-(2-Methylphenyl)-1H-tetrazole-5-thiol; 1-(o-Tolyl)-1H-tetrazole-5-thiol; 5-Thiol-1-o-tolyltetrazole; o-Tolyltetrazolethiol; 2-Methylphenyl-1H-tetrazole-5-thiol; TT-SH (common abbreviation); 1H-Tetrazole-5-thiol, 1-(2-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 1-o-Tolyl-1H-Tetrazole-5-Thiol is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its property of being easily oxidized, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation to maintain optimal purity and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.