Description

3-Chloro-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile is a versatile heterocyclic organic compound that serves as a critical building block in advanced chemical synthesis. Its unique fused-ring structure containing chlorine and nitrile functional groups makes it a valuable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex isoquinoline and tetrahydroisoquinoline derivatives.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.
• Chemical Reference Standard: Supplied to analytical laboratories for method development and quality control testing.

Basic Information

Product Name	3-Chloro-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile
CAS No.	53661-33-9
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	3-Chloro-5,6,7,8-tetrahydro-4-isoquinolinecarbonitrile; 4-Cyano-3-chloro-5,6,7,8-tetrahydroisoquinoline; 3-Chloro-4-cyano-5,6,7,8-tetrahydroisoquinoline; 5,6,7,8-Tetrahydro-3-chloro-4-isoquinolinecarbonitrile; 3-Chloro-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile; 53661-33-9; 3-Chloro-4-cyano-5,6,7,8-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our 3-Chloro-5,6,7,8-Tetrahydroisoquinoline-4-Carbonitrile is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.