Description

2H-Isoindole-2-Acetic Acid, .Alpha.-Butyl-1,3-Dihydro-1,3-Dioxo-, (.Alpha.S)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its specific stereochemistry and functional groups, which make it a critical building block for constructing complex molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active ingredients and novel chemical entities. CAS No. 53624-77-4.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the synthesis of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry is crucial for bioactivity.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new asymmetric catalytic reactions.
• Fine Chemical Production: Acts as a specialized building block for the custom synthesis of complex, high-value fine chemicals and other advanced intermediates.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, ligands for metal-organic frameworks (MOFs), or other functional materials requiring specific molecular architectures.

Basic Information

Product Name	2H-Isoindole-2-Acetic Acid, .Alpha.-Butyl-1,3-Dihydro-1,3-Dioxo-, (.Alpha.S)-
CAS No.	53624-77-4
Molecular Formula	C14H15NO4
Molecular Weight	261.27 g/mol
Synonyms	(S)-α-Butyl-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid; (S)-N-Phthaloyl-2-aminopentanoic acid; (S)-2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)pentanoic acid; (αS)-α-Butyl-1,3-dihydro-1,3-dioxo-2H-isoindole-2-acetic acid; (S)-N-Phthaloyl-2-aminocaprylic acid derivative; (S)-Phthaloylaminopentanoic acid; (S)-2-Phthalimidopentanoic acid
EINECS	Contact for details

Quality Control

Our 2H-Isoindole-2-Acetic Acid, .Alpha.-Butyl-1,3-Dihydro-1,3-Dioxo-, (.Alpha.S)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications and industry best practices. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.