Description

(R)-1,2,3,4-Tetrahydro-1-Methyl-6,7-Isoquinolinediol is a chiral isoquinoline derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a critical chiral building block and synthetic intermediate for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for applications in asymmetric synthesis, medicinal chemistry, and process development. The product is supplied with a high level of purity and batch-to-batch consistency to meet stringent research and development needs.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or building block for designing and screening novel therapeutic compounds in drug discovery programs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or reagent in stereoselective chemical reactions to create enantiomerically pure products.
• Biochemical Research: Potential tool compound for studying enzyme interactions and biological pathways related to catecholamine systems.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, agrochemicals, and performance materials requiring specific stereochemistry.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R)-1,2,3,4-Tetrahydro-1-Methyl-6,7-Isoquinolinediol
CAS No.	53622-83-6
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-1,2,3,4-Tetrahydro-1-methyl-6,7-isoquinolinediol; (R)-1-Methyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline; (R)-6,7-Dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline; (R)-1-Methyl-1,2,3,4-tetrahydro-6,7-isoquinolinediol; (R)-1-Methyl-6,7-isoquinolinediol; (R)-1-Methyl-6,7-dihydroxytetrahydroisoquinoline; (R)-1-Methyl-6,7-dihydroxy-THIQ; (R)-6,7-Dihydroxy-1-methyl-THIQ
EINECS	Contact for details

Quality Control

Our (R)-1,2,3,4-Tetrahydro-1-Methyl-6,7-Isoquinolinediol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep the container tightly sealed in a dry environment to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.