Description

Tramadol Hydrochloride is a synthetic opioid analgesic of the aminocyclohexanol group. It is a centrally acting pain reliever that binds to μ-opioid receptors and inhibits the reuptake of norepinephrine and serotonin. This product is essential for the formulation of effective pain management medications. It is primarily required by pharmaceutical manufacturers and research institutions developing analgesic drugs for moderate to moderately severe pain.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of prescription analgesic tablets, capsules, and oral solutions.
• Generic Drug Formulation: Key component in the production of generic tramadol hydrochloride medications.
• Clinical Research: Used as a reference standard or active compound in pharmacological and pain management studies.
• Veterinary Medicine: Formulated for pain relief in animals under strict veterinary supervision.
• Controlled-Release Formulations: Incorporated into advanced drug delivery systems for prolonged analgesic effect.

Basic Information

Product Name	Tramadol Hydrochloride
CAS No.	53611-16-8
Molecular Formula	C16H25NO2 • HCl
Molecular Weight	299.84 g/mol
Synonyms	(±)-cis-2-[(Dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol Hydrochloride; Tramadol HCl; Tramal; Ultram; Tradol; Contramal; Zydol; Crispin; Ralivia; Ryzolt
EINECS	Contact for details

Quality Control

Our Tramadol Hydrochloride is manufactured and tested under strict quality management systems. It meets high-purity standards suitable for pharmaceutical applications. Comprehensive testing includes identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) is provided with each batch, detailing compliance with in-house specifications. We support audits and can provide documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.5% (on anhydrous basis)
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.15%, Total impurities ≤ 0.5%
Optical Rotation	-0.10° to +0.10°

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.