Description

2-(3,4-Dihydroxyphenyl-D3)Ethylamine Hcl is a deuterated isotopologue of dopamine hydrochloride, where three hydrogen atoms are replaced with deuterium. This compound is crucial for advanced research and development, particularly in analytical chemistry and pharmacology, where it serves as a stable, non-radioactive internal standard. It is primarily needed by pharmaceutical R&D laboratories, analytical testing facilities, and academic institutions engaged in metabolic studies, pharmacokinetics, and neurochemical research.

Application

• Internal Standard for LC-MS/MS: Used as a high-purity, stable isotope-labeled internal standard for the precise quantification of dopamine and related catecholamines in complex biological matrices via mass spectrometry.
• Pharmacokinetic & Metabolic Studies: Enables accurate tracking of drug metabolism, absorption, and distribution in vivo without interference from endogenous compounds.
• Neurochemical Research: Supports investigations into dopamine pathways, receptor binding assays, and neurotransmitter dynamics in neurological disease models.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of process-related impurities or degradation products in active pharmaceutical ingredient (API) manufacturing.
• Clinical Diagnostics Development: Facilitates the creation of robust and reliable diagnostic assays for measuring catecholamine levels in clinical samples.

Basic Information

Product Name	2-(3,4-Dihydroxyphenyl-D3)Ethylamine Hcl
CAS No.	53587-30-7
Molecular Formula	C8H8D3ClNO2
Molecular Weight	202.68 g/mol
Synonyms	Dopamine-d3 Hydrochloride; 2-(3,4-Dihydroxyphenyl-d3)ethylamine Hydrochloride; 4-(2-Aminoethyl)-1,2-benzenediol-d3 Hydrochloride; 3,4-Dihydroxyphenethylamine-d3 HCl; 3-Hydroxytyramine-d3 Hydrochloride; DA-d3 HCl; (2-2H3)Dopamine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dihydroxyphenyl-D3)Ethylamine Hcl is manufactured under strict quality control protocols to ensure high isotopic purity and chemical integrity, suitable for sensitive analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment, chemical purity, and absence of critical impurities. We are committed to meeting the stringent requirements of research and pharmaceutical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.