Description

2-Methyl-3-thiophenecarboxylic acid methyl ester is a high-purity heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing novel thiophene-based scaffolds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for enhanced bioactivity and environmental profile.
• Material Science Precursor: Serves as a monomer or building block for conductive polymers and organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis, facilitating asymmetric synthesis and cross-coupling reactions.
• Flavor and Fragrance Industry: Acts as an intermediate for creating complex sulfur-containing aroma chemicals, contributing to savory or roasted notes in advanced flavor formulations.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for client-specific molecules.

Basic Information

Product Name	2-Methyl-3-thiophenecarboxylic Acid Methyl Ester
CAS No.	53562-51-9
Molecular Formula	C7H8O2S
Molecular Weight	156.20 g/mol
Synonyms	Methyl 2-methyl-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2-methyl-, methyl ester; 2-Methyl-3-methoxycarbonylthiophene; Methyl 2-methylthiophene-3-carboxylate; 2-Methyl-thiophene-3-carboxylic acid methyl ester; 3-Carbomethoxy-2-methylthiophene
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-3-thiophenecarboxylic Acid Methyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and commercial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom specifications can be developed to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at controlled room temperature for shorter periods. Keep container tightly sealed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.