Description

1-O,2-O,3-O,4-O,5-o-Pentakis(trimethylsilyl)-α-D-fructopyranose is a fully silylated derivative of fructose, a key protected intermediate in synthetic carbohydrate chemistry. This compound is critical for researchers and manufacturers requiring precise control over fructose reactivity and solubility in non-polar environments. It is primarily utilized in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex molecules, nucleosides, and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block for the synthesis of novel nucleoside analogs, prodrugs, and other bioactive sugar-containing compounds.
• Glycochemistry Research: Used as a protected fructose donor in glycosylation reactions and the study of carbohydrate-protein interactions.
• Agrochemical Synthesis: Acts as a precursor in the development of sugar-based surfactants, adjuvants, and active ingredients.
• Material Science: Employed in the creation of specialized polymers, coatings, and dendrimers with tailored properties.
• Analytical Standard: Provides a high-purity reference standard for chromatographic analysis (GC, HPLC) and method validation in quality control laboratories.
• Process Chemistry: Enables scalable synthesis routes where the trimethylsilyl groups offer temporary protection for specific hydroxyl functionalities.

Basic Information

Item	Details
Product Name	1-O,2-O,3-O,4-O,5-o-Pentakis(trimethylsilyl)-α-D-fructopyranose
CAS No.	53538-02-6
Molecular Formula	C21H52O6Si5
Molecular Weight	553.06 g/mol
Synonyms	Pentakis-O-(trimethylsilyl)-α-D-fructopyranose; α-D-Fructopyranose, pentakis-O-(trimethylsilyl)-; 1,2,3,4,5-Penta-O-trimethylsilyl-α-D-fructopyranose; TMS-fructose; Fully silylated fructose; α-D-Fructose pentakis(trimethylsilyl) ether; Per-O-trimethylsilyl-α-D-fructopyranose
EINECS	Contact for details

Quality Control

Every batch of 1-O,2-O,3-O,4-O,5-o-Pentakis(trimethylsilyl)-α-D-fructopyranose is manufactured under strict quality management systems. We employ advanced analytical techniques including NMR, GC, and HPLC to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.