Description

(R)-(-)-2,2,2-Trifluoro-1-(9-Anthryl)Ethanol is a high-purity, chiral fluorinated alcohol derivative of anthracene, serving as a crucial chiral auxiliary and resolving agent in asymmetric synthesis. Its unique structure provides exceptional stereoselectivity in chemical reactions, making it invaluable for the production of enantiomerically pure compounds. This product is essential for research and development laboratories and production facilities in the pharmaceutical, agrochemical, and advanced materials sectors that require precise chiral control.

Application

• Chiral Resolution Agent: Used for the separation of enantiomers of racemic mixtures, particularly for acids and other functional groups via diastereomeric salt formation.
• Asymmetric Synthesis Auxiliary: Acts as a chiral controller in key synthetic steps, including alkylations, aldol reactions, and reductions to induce high enantiomeric excess.
• Pharmaceutical Intermediate: Employed in the research and scale-up synthesis of active pharmaceutical ingredients (APIs) where specific chirality is critical for biological activity.
• Ligand Precursor: Serves as a building block for the synthesis of chiral ligands used in asymmetric catalysis, such as transition metal complexes.
• Analytical Chemistry Standard: Utilized as a reference standard in chiral chromatography (HPLC, GC) for method development and calibration.
• Agrochemical Research: Applied in the development of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Material Science: Investigated for the creation of chiral dopants or building blocks in liquid crystals and other functional organic materials.

Basic Information

Item	Detail
Product Name	(R)-(-)-2,2,2-Trifluoro-1-(9-Anthryl)Ethanol
CAS No.	53531-34-3
Molecular Formula	C₁₆H₁₁F₃O
Molecular Weight	276.25 g/mol
Synonyms	(R)-(-)-2,2,2-Trifluoro-1-(9-Anthryl)Ethanol; (R)-1-(9-Anthryl)-2,2,2-trifluoroethanol; (R)-TFAE; (R)-α-(Trifluoromethyl)-9-anthracenemethanol; (R)-1-(Anthracen-9-yl)-2,2,2-trifluoroethanol; (R)-9-Anthryltrifluoromethylcarbinol; (R)-ATFC; Pirkle's Alcohol (R)-enantiomer
EINECS	Contact for details

Quality Control

Our (R)-(-)-2,2,2-Trifluoro-1-(9-Anthryl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a dry environment and sealed immediately after use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.