Description

1H-Indole-2-Thiol, 1-Methyl- CAS NO 53497-48-6 is a specialized sulfur-containing heterocyclic compound that serves as a versatile building block in advanced organic synthesis. Its unique indole-thiol structure makes it a critical intermediate for developing novel pharmaceuticals and functional materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new active molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of new generation pesticides and fungicides due to its bioactive indole core.
• Material Science: Building block for creating organic semiconductors, conductive polymers, and advanced ligands for catalysis.
• Chemical Research: A valuable reagent for studying thiol-indole chemistry and developing new synthetic methodologies.
• Bioconjugation: Potential use in bioconjugation chemistry and the development of probe molecules for biochemical assays.

Basic Information

Product Name	1H-Indole-2-Thiol, 1-Methyl- CAS NO 53497-48-6
CAS No.	53497-48-6
Molecular Formula	C9H9NS
Molecular Weight	163.24 g/mol
Synonyms	1-Methyl-1H-indole-2-thiol; 1-Methylindole-2-thiol; 2-Mercapto-1-methylindole; 1-Methyl-2-mercaptoindole; 1-Methylindole-2-thione (tautomer); 53497-48-6; 1-Methyl-1H-indole-2-thione
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and industrial use. We employ advanced analytical techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 15-25°C. Due to its sensitivity to oxidation and light, minimize exposure to air and ambient light during handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.