Description

(3S,16S)-17α,21-Epoxy-14,15-Dihydro-14α-Hydroxy-12-Methoxyeburnamenine-14-Carboxylic Acid Methyl Ester CAS NO 53492-09-4 is a high-purity, complex indole alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical advanced intermediate or reference standard for the synthesis and study of pharmacologically active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical manufacturing.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new drug candidates.
• Biochemical Research: Investigated for its potential biological activity and interaction with various enzyme systems.
• Process Development: Utilized in scaling up synthetic routes for the production of target molecules in kilo-lab and pilot plant settings.

Basic Information

Product Name	(3S,16S)-17α,21-Epoxy-14,15-Dihydro-14α-Hydroxy-12-Methoxyeburnamenine-14-Carboxylic Acid Methyl Ester
CAS No.	53492-09-4
Molecular Formula	C22H26N2O5
Molecular Weight	398.46 g/mol
Synonyms	12-Methoxyeburnamenine-14-carboxylic acid methyl ester derivative; Vincamine alkaloid derivative; (3S,16S)-14α-Hydroxy-12-methoxy-17α,21-epoxy-14,15-dihydroeburnamenine-14-carboxylic acid methyl ester; Eburnamenine-14-carboxylic acid, 14,15-dihydro-14α-hydroxy-12-methoxy-17α,21-epoxy-, methyl ester, (3S,16S)-; Methyl (3S,16S)-17α,21-epoxy-14,15-dihydro-14α-hydroxy-12-methoxyeburnamenine-14-carboxylate
EINECS	Contact for details

Quality Control

Our (3S,16S)-17α,21-Epoxy-14,15-Dihydro-14α-Hydroxy-12-Methoxyeburnamenine-14-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under inert atmosphere at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.