Description

3-Hydroxy-4-Oxobutyl-1-Phosphonate is a versatile organophosphorus compound with a unique structure that combines a phosphonate group with a hydroxyl and ketone functionality. This molecular architecture makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and life sciences industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of bisphosphonate drugs and other bioactive molecules targeting bone metabolism.
• Agrochemical Synthesis: Used in the development of novel herbicides and plant growth regulators that utilize phosphonate chemistry.
• Ligand and Chelating Agent Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal ion sequestration.
• Flame Retardant Additive Research: Investigated as a potential component or synergist in flame-retardant formulations for polymers.
• Material Science: Employed in the research of functionalized surfaces, coatings, and metal-organic frameworks (MOFs).
• Bioconjugation Chemistry: Utilized for modifying biomolecules due to its reactive sites that can be selectively functionalized.

Basic Information

Product Name	3-Hydroxy-4-Oxobutyl-1-Phosphonate
CAS No.	53478-18-5
Molecular Formula	C4H9O5P
Molecular Weight	168.09 g/mol
Synonyms	1-Hydroxy-3-oxobutylphosphonic Acid; 3-Oxo-4-hydroxybutylphosphonic Acid; 4-Hydroxy-3-oxobutylphosphonic Acid; (3-Hydroxy-4-oxobutyl)phosphonic Acid; 1-Hydroxy-3-oxobutane-1,1-diylbis(phosphonic Acid) (tautomeric form); Phosphonoacetic Acid, Acetonyl-; Acetonylphosphonic Acid Derivative
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Oxobutyl-1-Phosphonate is manufactured under a strict quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications typically meeting or exceeding research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/NMR), and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.