Description

Ethyl 3-Methyl-2-Butenoate-D6 is a deuterated analog of the corresponding ester, serving as a critical stable isotope-labeled internal standard for precise quantitative analysis. This high-purity compound is essential for ensuring accuracy and reliability in sensitive analytical techniques, particularly in regulated environments. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, agrochemical, and environmental science sectors for method development, validation, and trace-level quantification.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a deuterium-labeled reference compound in GC-MS and LC-MS/MS analyses to correct for variations in sample preparation and instrument response.
• Pharmaceutical Metabolism and Pharmacokinetics (DMPK): Enables accurate tracking and quantification of drug metabolites in biological matrices during ADME (Absorption, Distribution, Metabolism, and Excretion) studies.
• Environmental Analysis: Facilitates the detection and measurement of trace levels of related esters or degradation products in environmental samples.
• Food and Flavor Chemistry Research: Acts as a stable isotope tracer in studies investigating the biosynthesis or stability of flavor compounds and esters.
• Chemical Synthesis Research: Employed as a labeled building block or tracer in synthetic pathways to study reaction mechanisms or isotopic effects.
• Forensic and Toxicology Testing: Provides a reliable reference for the quantitative analysis of specific compounds in complex forensic or toxicological samples.

Basic Information

Product Name	Ethyl 3-Methyl-2-Butenoate-D6
CAS No.	53439-15-9
Molecular Formula	C7H6D6O2
Molecular Weight	134.21 g/mol (deuterated form)
Synonyms	Ethyl 3-Methyl-2-butenoate-d6; Ethyl 3-Methylcrotonate-d6; Ethyl β,β-Dimethylacrylate-d6; 3-Methyl-2-butenoic Acid Ethyl Ester-d6; Deutero Ethyl 3-Methyl-2-Butenoate; Ethyl Senecioate-d6; [D6]-Ethyl 3-Methyl-2-butenoate; Ethyl (E)-3-Methyl-2-butenoate-d6
EINECS	Contact for details

Quality Control

Our Ethyl 3-Methyl-2-Butenoate-D6 is manufactured under strict quality systems to ensure the high isotopic purity and chemical integrity required for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic methods, including NMR, GC-MS, and HPLC, to confirm isotopic enrichment and chemical purity. A comprehensive Certificate of Analysis (COA) detailing assay, isotopic purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Clear Colorless to Pale Yellow Liquid
Identification (IR / NMR)	Conforms to Reference Spectrum
Assay (GC / HPLC)	≥ 98.0% (Chemical Purity)
Isotopic Purity (MS)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Evaporation	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.