Description

1-Chloro-4-Methanesulfonylbutane is a versatile bifunctional organic intermediate containing both a reactive chloroalkyl group and a methanesulfonyl (mesyl) moiety. This dual functionality makes it a valuable building block for the synthesis of more complex molecules in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists for constructing sulfonamide derivatives, nucleophilic substitution reactions, and as a linker in medicinal chemistry.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing sulfonamide or alkylsulfone functional groups.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the chloro and mesyl groups facilitate further chemical modifications.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for specialty polymers, imparting specific solubility or reactivity characteristics.
• Ligand and Catalyst Preparation: Employed in the development of novel ligands for metal catalysis and organocatalysts.
• Chemical Research: A useful reagent for organic synthesis, enabling nucleophilic substitution reactions to introduce the butanesulfonyl moiety.
• Material Science: Potential precursor for surface modification agents and advanced functional materials.

Basic Information

Product Name	1-Chloro-4-Methanesulfonylbutane
CAS No.	53394-82-4
Molecular Formula	C5H11ClO2S
Molecular Weight	170.66 g/mol
Synonyms	4-(Methanesulfonyl)butyl chloride; 4-Chlorobutyl methyl sulfone; 1-Chloro-4-(methylsulfonyl)butane; Butane, 1-chloro-4-(methylsulfonyl)-; Methyl 4-chlorobutyl sulfone; 4-Methanesulfonylbutyl chloride
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Methanesulfonylbutane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by GC/HPLC), identity (IR/NMR), and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly closed when not in use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.