Description

Ethyl 2-Iodo-4-Methylthiazole-5-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive iodine and ester functionalities, which enable precise molecular construction in complex chemical environments. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel thiazole-containing drug candidates, particularly for antiviral, anti-inflammatory, and anticancer research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiazole core for biological activity.
• Material Science Research: Serves as a building block for creating functional organic materials, such as ligands for catalysis or components in organic electronics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.

Basic Information

Product Name	Ethyl 2-Iodo-4-Methylthiazole-5-Carboxylate
CAS No.	53137-15-8
Molecular Formula	C7H8INO2S
Molecular Weight	297.11 g/mol
Synonyms	5-Carbethoxy-2-iodo-4-methylthiazole; Ethyl 5-Iodo-4-methylthiazole-2-carboxylate; 2-Iodo-4-methyl-1,3-thiazole-5-carboxylic acid ethyl ester; Ethyl 2-iodo-4-methyl-1,3-thiazole-5-carboxylate; 4-Methyl-2-iodothiazole-5-carboxylic Acid Ethyl Ester; 2-Iodo-4-methylthiazole-5-carboxylic Acid Ethyl Ester; 5-Ethoxycarbonyl-2-iodo-4-methylthiazole
EINECS	Contact for details

Quality Control

Our Ethyl 2-Iodo-4-Methylthiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, minimize exposure during handling and transfer.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.