Description

(1-Aminoethyl)Phosphonic Acid Bis(Trimethylsilyl) Ester is a silylated derivative of a key aminophosphonic acid, serving as a versatile protected intermediate in advanced organic synthesis. This compound is particularly valuable for its role in introducing the phosphonic acid functional group under mild conditions, enabling the synthesis of complex molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing bioactive compounds, metal chelators, and flame retardants.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel drug candidates, particularly those targeting bone diseases or acting as enzyme inhibitors.
• Agrochemical Synthesis: Serves as a key building block for creating herbicides and plant growth regulators with phosphonate activity.
• Ligand and Chelator Precursor: Employed in the preparation of specialized ligands for catalysis and metal ion sequestration.
• Material Science: Acts as a monomer or additive in the development of flame-retardant polymers and advanced functional materials.
• Peptide Mimetics Research: Utilized to incorporate non-hydrolyzable phosphonate analogs of amino acids into peptides.
• Surface Modification Agent: Applied in the functionalization of surfaces for improved adhesion or specific chemical properties.

Basic Information

Item	Details
Product Name	(1-Aminoethyl)Phosphonic Acid Bis(Trimethylsilyl) Ester
CAS No.	53121-99-6
Molecular Formula	C8H24NO3PSi2
Molecular Weight	269.42 g/mol
Synonyms	1-Aminoethylphosphonic Acid Bis(trimethylsilyl) Ester; (1-Aminoethyl)phosphonic Acid Bis-O-(trimethylsilyl) Ester; Phosphonic Acid, P-(1-aminoethyl)-, bis(trimethylsilyl) ester; AEAP Bis(TMS) Ester; Aminoethylphosphonate TMS Ester; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1-Aminoethyl)Phosphonic Acid Bis(Trimethylsilyl) Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.