Description

2-Bromo-4-Methylthiophene is a versatile brominated heterocyclic building block, essential for constructing complex molecular architectures in advanced organic synthesis. Its core value lies in enabling precise functionalization and serving as a key precursor for materials with tailored electronic and photophysical properties. This high-purity intermediate is critically needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the thiophene moiety contributes to biological activity.
• Organic Electronic Materials: Serves as a key monomer or precursor for conductive polymers, organic semiconductors, and OLED (Organic Light-Emitting Diode) materials.
• Ligand and Catalyst Development: Employed in the design of novel ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Functional Dye and Pigment Production: Acts as an intermediate for creating specialized dyes, pigments, and imaging agents with specific light-absorption characteristics.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form complex biaryl and conjugated systems.

Basic Information

Product Name	2-Bromo-4-Methylthiophene
CAS No.	53119-60-1
Molecular Formula	C5H5BrS
Molecular Weight	177.06 g/mol
Synonyms	4-Methyl-2-bromothiophene; 2-Bromo-4-methylthiophene; 2-Bromo-4-methyl-thiophene; Thiophene, 2-bromo-4-methyl-; 4-Methyl-2-bromothiofene; 2-Brom-4-methylthiophen; 2-Bromo-4-methylthiofene; Bromo-methylthiophene
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Methylthiophene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and impurity profiles via validated methods such as GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.